The show is a parody of the reality TV series Big Brother, with a similar plot. The seven very different contestants share a mansion "Somewhere in Saskatchewan..." where they compete in challenges to avoid extinction (the show's version of disqualification), supervised by the show's host, Claude the vulture in the first season, and later Bobbie the seal in the second. Despite being eliminated, characters always come back the next episode, as Life's a Zoo does not use continuity, although this changes in the second season. Additionally, each episode features a specially edited music video from a different artist. The show won Best Animated Series at the Canadian Gemini Awards in 2009.